PTFE or Polytetrafluoroethylene membranes are extensively used for the filtration of gaseous and organic HPLC solvents. Also, this hydrophobic membrane can be used for clarification of corrosive substances. It has low extractables and it is chemically resistant to most of the substances. Selection of the right membrane should be ideally based on the application. Here are the things that you must know for choosing the best PTFE syringe filters.

Applications of PTFE Filters:

The typical applications of these filters include sterile filtration, clarification, sample preparation, and medical applications. They are available in varied pore sizes to suit every application. They are applicable for dissolution testing, routine QC analysis, content uniformity, biofuel analysis, food analysis, environmental samples, and removing the protein precipitates.

The Features of PTFE Filters:

The hydrophobic syringe filters are used in applications that require pre-wetting of the membrane, specifically for low surface tension substances like alcohols. They can be used for filtration of aqueous solutions due to their compatibility. These filters can be sterilized using the autoclaving at 125 degrees for 15 minutes. Most importantly, they offer exceptional temperature stability.

Minimum Hold-Up Volume:

The PTFE syringe filters have a low hold-up volume. It means that the sample recovery is maximized with these filters. When buying these filters, you should check its retention volume.


These filters are compatible with most of the chemical substances and diverse applications. This versatility makes them a viable choice for diversified filtration needs. It can offer interference-free chemical determinations.

Optimized Throughput:

Due to their maximized membrane support, these filters offer optimum throughput in every application.

Easy Sample Delivery:

These syringe filters have a Leur lock inlet for secure fitting and Leur spike outlet for simplified sample delivery in the HPCL vials.

With its unique properties, PTFE filters are the prominent choice for many size-selective samples. It can be used for gravimetric, microscopic, or chemical analysis of a particulate matter. They have a PMP support ring that facilitates low back pressure for long sampling procedures at higher flow rates.

How To Buy The Best PTFE Filters?

There are many important factors that must be analyzed for buying these filters. Here, they are:

The Pore Size:

You must choose the pore size according to the sample passing through the filters. The filter with pore size of 0.2 micron is perfect for sterile venting. For transducers protection in gas or air filtration, you may opt for filters with pore sizes ranging from 1.0 to 0.45 micron.

Check the Label:

The trusted manufacturers have their syringe filters marked with membrane material and pore size for their easy identification.

When looking to buy PTFE syringe filters for your filtration needs, assess them on all these parameters and prefer the products that are competitively priced.