Syringe filters are helpful for fast and efficient filtration. Selection of syringe filter should be according to application. The use of syringe filters is in a sterile solution or a clarified sterile solution. On the other hand, nonsterile syringe filters utilize for general filtration and sample purification. Simsii inc. is a supplier of syringe filters, membrane filters, etc. If you need membrane filters and syringe filters, then Simsii, inc. can help you.

How To Choose Syringe Filters

Users can set the size of the syringe filter with their sample. You must use a greater membrane area if you want to push the aqueous solution through it with high volume.

Here are some aspects of syringe filters that we should look at before selecting;

The Aperture

There are different apertures for syringe filters. Some ordinary ones are 0.2um and 0.45um for syringe filters. We recommend you use 0.2 or 0.1 if small and fine particles are in the sample. The centrifugal filters can also filter the little particle.

Filter Material

There are varieties of needle filter materials available. Some common materials are polyethersulfone cellulose acetate and polyamide. Be careful while choosing needle filters. Material can affect the effective filtration area or EFA and the capacity.

Filter Size

It is crucial to select a syringe filter to hold more fluid because as the particles start to accumulate, they can clog the pores and disable the filters. Large diameters provide high retention volumes. The amount of liquid left after using the filter is known as retention. Simsii recommends using filters of small diameters for rare and expensive fluids.

How To Use Syringe Filters

Here are some suggestions on using syringe filters. When you are handling high concentration samples and not concerned about low concentration.

1 Obtain suitable filters according to your sample.

2 You should inhale 1ml of air to take a sample in a sterile syringe.

3 Surge 1ml sample into a waste liquid container.

4 Evacuate the remaining sample into clean vials for storage.

5 Shove the first air into the same vial. It is necessary to push the remaining liquid and reduce the retained volume.

6 In the end, you must dispose of the filter and syringes properly.

7 There are other steps for taking samples when you are concerned about contamination.

8 Try to pick the most appropriate filter for use.

9 Soak 1ml of air cushion and 10ml of blank matrix respectively.

10 Pour out the air cushion and substrate into the waste container.

Can We Reuse Syringe Filters

You can use the Whatman syringe and syringeless filters only one time. It provides speed, performance, and convenience for single use. We will advise you to not reuse it because some particles that are not visible to the naked eye can cross-contamination and reduce the accuracy of the result.


In this blog, you will learn about the complete guide on syringe filters. There might be a question in your mind about what is syringe filter, how to use a membrane filter, and more. This blog can help you to reach the answer to your question. If you want to know more about membrane filters and syringe filters, simsii can help you.