Syringe filter is a disposable filter cartridges that is connected to the syringe end. Before utilizing high-performance liquid chromatography, it is typically employed to clean your sample (HPLC). They are an excellent addition to any lab because they are extremely reasonably priced and may also be used for general-purpose filtering. Below, we will discuss the significance and use of these tools.

A single-use, membrane-based tool called a syringe filter (or wheel filter) is used to filter out particle contaminants from tiny (less than 100 mL) liquid samples. Disposable syringe filters are frequently used in labs for quick and effective filtering, material purification, or even sterilization, depending on the desired end application.

Non-Sterile Syringe Filters vs. Sterile Syringe Filters

While the main purpose of a syringe filter is to remove particles from a liquid sample, depending on the ultimate use, you will either choose a sterile or non-sterile filter.

  • - Non-sterile fluids can be sterilized with sterile syringe filters, while sterile solutions can be made clearer. Discover more about sterile filters according to usage.
  • - Sample purification and general filtration are done with non-sterile syringe filters.
  • - Discover more information about non-sterile filters by use.

How to Use a Syringe Filter

Draw your sample into the syringe and then attach the filter to the syringe end after choosing the right syringe and filter for your sample and application. Make sure the leur lock filter is securely fastened into the syringe tip if you're using one. Push a few drips through the filter while holding the syringe with the filter pointed up to "top off."

By placing the filter tip over the collection container and gently applying positive pressure, the sample can be forced through a syringe filter. Remove the filter from the syringe and draw air into it to cleanse the filter and increase sample throughput. Reattach the filter after that, and then press the plunger to push some air through the filter.

The Best Syringe Filters to Choose

You can maximize your investment and improve the precision of your laboratory results by choosing the right syringe filter for your application. You should inquire into issues like Does my filter needs to be acid resistant? Which types of samples will I be working with? Check out the following recommendations to aid in your selection procedure.


Using a syringe filter is crucial for a few specific laboratory procedures to provide precise and trustworthy findings.

Using HPLC

Syringe filters are most frequently employed before HPLC analysis, as was already noted. This is because particles can readily harm an HPLC due to the high pressures and small bore they contain. You can prevent this by removing these particles with your syringe filter.

Water Samples

Nylon, PES, GHP, or PVDF Syringe Filters membranes are the best options for syringes with hydrophilic membranes when working with aqueous samples.

Filters for CellTreat Syringes

A syringe filter compatible with the substances your study will be using is crucial. Keep in mind that polymeric membranes have varying chemical compatibilities. Due to variations in chemical compatibility and hydrophobicity/hydrophilicity, one type of syringe filter will typically not work with all applications, while some goods may have all-purpose uses.

Low Levels of Extractables

It's critical to select the appropriate filter for your application since, despite the fact that filters are intended to improve the accuracy of your trial results by removing impurities and undesired particles, employing the incorrect filter can actually have the opposite effect. Extractables from the filter may elute into your samples if an improper filter is used.

Inorganic solvents and gases

Hydrophobic membranes, like PTFE membranes, are excellent options for working with gases and organic solvents since they repel water and don't react with harsh organic So, these are some benefits of using a syringe filter. You can too use this essential syringe to take its benefits.